Psychoactive medications tend to be less effective and have more side effects if you take them patchily rather than regularly as prescribed. The idea is to maintain a fairly constant level of the drug in your system, not to create a whole new roller coaster. If the drugs you have aren't working for you, you need to go back to the doctor and discuss the problem. I went through something like four different antidepressants to find one that both worked and didn't have excessive side effects.
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